Investors & Media

Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 287 1,224.10 87.35 130,231,767
Mutual Fund 271 449.70 40.45 60,299,946
Insider 10 16.04 1.13 1,681,570

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 129 133.86 9.54 14,229,092
Sellers 146 -191.76 13.51 -20,141,695
Net -- -57.90 3.97 -5,912,603

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 1,224.10 87.35 130,231,767
Top 10 Inst. 766.92 54.32 80,984,035
Top 20 Inst. 962.28 68.16 101,613,839
Top 50 Inst. 1,133.37 80.78 120,434,884

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 57 154.11 10.92 16,285,289
Aggressive Growth 4 3.07 0.22 325,453
Core Growth 37 61.17 4.34 6,476,605
Growth 16 89.87 6.36 9,483,231
Income 8 6.58 0.47 703,981
Income Value 2 3.95 0.28 417,058
Yield 6 2.64 0.19 286,923
Index 31 340.12 24.11 35,942,938
Other 86 641.74 46.13 68,774,906
Broker Dealer 21 55.64 3.94 5,875,637
GARP 32 282.12 20.64 30,770,768
Hedge Fund 29 165.91 11.77 17,549,357
Sector Specific 2 130.48 9.24 13,778,224
Specialty 2 7.58 0.54 800,920
Value 35 42.27 3.08 4,591,073
Core Value 27 17.68 1.34 1,994,822
Deep Value 8 24.59 1.74 2,596,251

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Redmile Group, LLC 12,309,035 8.26 -6,907 9/30/18
BlackRock Institutional Trust Company, N.A. 10,654,231 7.15 1,000,483 9/30/18
The Vanguard Group, Inc. 10,158,434 6.81 390,917 9/30/18
State Street Global Advisors (US) 8,931,512 5.99 -64,495 9/30/18
ClearBridge Investments, LLC 8,083,851 5.42 -1,081,179 9/30/18
Fidelity Management & Research Company 7,477,197 5.02 -1,204,937 9/30/18
Capital Research Global Investors 7,095,570 4.76 -2,335,430 9/30/18
Renaissance Technologies LLC 6,312,640 4.23 -212,660 9/30/18
Point72 Asset Management, L.P. 6,172,765 4.14 4,116,832 9/30/18
PRIMECAP Management Company 3,788,800 2.54 -34,500 9/30/18
Nuveen LLC 3,647,973 2.45 157,547 9/30/18
Voya Investment Management LLC 2,424,017 1.63 574,761 9/30/18
Citadel LLC 2,305,676 1.55 437,848 9/30/18
T. Rowe Price Associates, Inc. 2,270,747 1.52 -628,364 9/30/18
Morgan Stanley & Co. LLC 1,993,408 1.34 -716,230 9/30/18
ArrowMark Colorado Holdings, LLC 1,927,950 1.29 1,927,950 9/30/18
Northern Trust Investments, Inc. 1,676,983 1.12 190,210 9/30/18
Geode Capital Management, L.L.C. 1,620,786 1.09 102,624 9/30/18
OrbiMed Advisors, LLC 1,469,189 0.99 -1,435,081 9/30/18
Wells Fargo Advisors 1,293,075 0.87 -89,483 9/30/18
Goldman Sachs & Company, Inc. 1,259,806 0.84 -259,429 9/30/18
Jennison Associates LLC 1,173,360 0.79 8,717 9/30/18
Candriam Belgium S.A. 1,012,500 0.68 60,000 10/31/18
Candriam Luxembourg S.A. 952,500 0.64 258,500 9/30/18
Pinnacle Associates Ltd. 942,180 0.63 -154,757 9/30/18
BNP Paribas Asset Management USA, Inc. 937,835 0.63 937,835 9/30/18
PanAgora Asset Management Inc. 936,788 0.63 33,481 9/30/18
Enyedy (Mark J) 921,383 0.62 389,000 4/23/18
Charles Schwab Investment Management, Inc. 871,837 0.58 105,881 9/30/18
Millennium Management LLC 837,142 0.56 579,938 9/30/18
Morgan Stanley Wealth Management 809,299 0.54 -4,256 9/30/18
Managed Account Advisors LLC 799,920 0.54 -22,301 9/30/18
BNP Paribas Asset Management UK Limited 665,124 0.45 27,733 10/31/18
Macquarie Investment Management 650,000 0.44 -480,000 9/30/18
Raymond James & Associates, Inc. 648,833 0.44 75 9/30/18
Allianz Global Investors U.S. LLC 473,846 0.32 -286,941 9/30/18
BlackRock Investment Management, LLC 449,020 0.30 42,198 9/30/18
Deutsche Asset Management Americas 433,895 0.29 202,374 9/30/18
Medical Strategy GmbH 429,870 0.29 77,500 10/31/18
Marshall Wace LLP 427,000 0.29 427,000 9/30/18
BNY Mellon Asset Management 392,974 0.26 54,818 9/30/18
Gregory (Richard J) 386,844 0.26 147,753 4/23/18
Numeric Investors LLC 359,200 0.24 351,900 9/30/18
Norges Bank Investment Management (NBIM) 333,979 0.22 -- 12/31/17
Johnston David Brannon 303,940 0.20 123,250 6/6/18
Granahan Investment Management, Inc. 302,000 0.20 -- 3/31/18
J. Goldman & Co., L.P. 296,113 0.20 296,113 9/30/18
First Trust Advisors L.P. 285,406 0.19 -84,122 9/30/18
BlackRock Financial Management, Inc. 264,740 0.18 -6,637 9/30/18
Alps Advisors, Inc. 263,711 0.18 70,640 9/30/18

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